South Carolina • 59 Listings • Updated Daily

Dental Practices for Sale in South Carolina

There are 59 dental practices for sale in South Carolina (SC) on The Dental Practice Market across 6 specialties, carried by 15 different sources. Listings are aggregated from brokers nationwide and state dental associations, re-verified daily, and anonymized to protect sellers.

Free · No registration · Updated dailyData as of . Refreshed from broker sources daily.

South Carolina has 59 dental practices publicly listed for sale on The Dental Practice Market, carried by 15 brokerages and dental association classifieds. The mix is General Dentistry (49), Periodontics (3), Endodontics (3) and Oral Surgery (2), plus 2 other specialties. Inventory spreads across 32 cities, 3 of which have enough current listings for a page of their own — Columbia (5), Florence (3) and Charleston (3). 1 listing mentions the building or suite being available with the practice. 3 were first published in the last 30 days, excluding days a new source was onboarded. Every listing links back to the broker holding it; the practice name and address stay with that broker until you sign their confidentiality agreement.

New in South Carolina in the last 7 days

1 practice was first published by its broker in the last 7 days. Days a new source was onboarded are not counted. Data as of Oct 22, 2026.

General Dentistry practice, South Carolina

Practice types for sale in South Carolina

General Dentistry (SC)49Periodontics (SC)3Endodontics (SC)3Oral Surgery (SC)2

Cities in South Carolina

3 South Carolina cities have three or more practices listed right now. Each has its own page.

Columbia, SC5Florence, SC3Charleston, SC3
Columbia, SC
Price not published · $3,000,000 collections
General Dentistry
Price not published

Columbia, South Carolina - General - Sale of Practice

$3,000,000
Collections
8
Operatories
3,000
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
Metro Columbia, SC
Price not published · $2,300,000 collections
General Dentistry
Price not published

Metro Columbia, SC

$2,300,000
Collections
10
Operatories
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Columbia, SC
Price not published · $2,250,000 collections
General Dentistry
Price not published

Columbia, SC

$2,250,000
Collections
7
Operatories
3,627
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Beaufort County, SC
$1,100,000 · $1,450,000 collections
General Dentistry
$1,100,000

Beaufort County, SC

$1,450,000
Collections
5
Operatories
2,700
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Florence, SC
Price not published · $1,300,000 collections
General Dentistry
Price not published

Florence, South Carolina - General - Partnership, Associateship

$1,300,000
Collections
5
Operatories
2,864
Patients
More photos and details at Heather Asbury →
Offered by
Heather Asbury
Verified today
Charlotte, SC
Price not published · $1,270,000 collections
General Dentistry
Price not published

For Sale Well Established GDP Between Charlotte and Greenville

$1,270,000
Collections
9
Operatories
Listed on scda.org →
Verified today
Charleston Area, SC
$700,000 · $1,100,000 collections
General Dentistry
$700,000

General Dentistry — Charleston Area

$1,100,000
Collections
4
Operatories
2,860
Patients
More photos and details at Henry Schein DPT →
Verified today
Midlands Region, SC
Price not published · $1,000,000 collections
General Dentistry
Price not published

Midlands Region, SC

$1,000,000
Collections
4
Operatories
2,600
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Greenville-Spartanburg, SC
Price not published · $1,000,000 collections
Periodontics
Price not published

Practice For Sale Greenville-Spartanburg

$1,000,000
Collections
4
Operatories
2,200
Sq Ft
Listed on scda.org →
Offered by
McGill & Lyon
Verified today
Florence, SC
Price not published · $914,000 collections
General Dentistry
Price not published

General - Sale of Practice

$914,000
Collections
5
Operatories
450
Patients
More photos and details at Mara Saucedo →
Offered by
Mara Saucedo
Verified today
Spartanburg, SC
Price not published · $900,000 collections
General Dentistry
Price not published

Spartanburg, South Carolina - General - Sale of Practice

$900,000
Collections
5
Operatories
2,400
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
Central South Carolina
Price not published · $850,000 collections
Endodontics
Price not published

Central, South Carolina - Endodontics - Sale of Practice

$850,000
Collections
2
Operatories
1,600
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
South Carolina
Price not published · $800,000 collections
General Dentistry
Price not published

Surrounding Myrtle Beach Area, SC

$800,000
Collections
8
Operatories
962
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Greenville, SC
Price not published · $800,000 collections
General Dentistry
Price not published

Greenville, South Carolina - General - Sale of Practice

$800,000
Collections
4
Operatories
815
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
South Carolina
Price not published · $800,000 collections
General Dentistry
Price not published

Red Bank & White Knoll, South Carolina - General - Sale of Practice

$800,000
Collections
3
Operatories
1,600
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
Greenville County, SC
$585,000 · $793,000 collections
Prosthodontics
$585,000

Prosthodontics — Greenville County

$793,000
Collections
4
Operatories
6,000
Sq Ft
More photos and details at Henry Schein DPT →
Verified today
East Columbia, SC
Price not published · $730,000 collections
General Dentistry
Price not published

East Columbia, South Carolina - General - Sale of Practice, Partnership

$730,000
Collections
3
Operatories
1,600
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
North Charleston, SC
Price not published · $718,000 collections
General Dentistry
Price not published

North Charleston, South Carolina - General - Sale of Practice

$718,000
Collections
6
Operatories
1,466
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
South Carolina
Price not published · $713,224 collections
General Dentistry
Price not published

General Dentistry practice, South Carolina, US,

$713,224
Collections
Listed on dentaltown.com →
Verified today
West Columbia, SC
Price not published · $660,000 collections
General Dentistry
Price not published

West Columbia, SC

$660,000
Collections
5
Operatories
2,067
Sq Ft
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
West Columbia Area, SC
Price not published · $585,000 collections
General Dentistry
Price not published

West Columbia Area, SC

$585,000
Collections
5
Operatories
1,583
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Columbia, SC
Price not published · $577,000 collections
General Dentistry
Price not published

Columbia, SC

$577,000
Collections
4
Operatories
2,480
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Greenwood County, SC
Price not published · $560,000 collections
General Dentistry
Price not published

Greenwood County, SC

$560,000
Collections
5
Operatories
1,337
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
East Columbia, SC
Price not published · $470,000 collections
General Dentistry
Price not published

East Columbia, South Carolina - General - Sale of Practice

$470,000
Collections
6
Operatories
890
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
Lexington County, SC
$583,000 · $465,000 collections
General Dentistry
$583,000

Lexington County, SC

$465,000
Collections
4
Operatories
850
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Spartanburg County, SC
Price not published · $400,000 collections
General Dentistry
Price not published

Spartanburg County, South Carolina - General - Sale of Practice

$400,000
Collections
3
Operatories
1,341
Patients
More photos and details at Neal McFadden →
Offered by
Neal McFadden
Verified today
Charleston - West Ashley, SC
Price not published · $330,000 collections
General Dentistry
Price not published

Charleston - West Ashley, SC

$330,000
Collections
3
Operatories
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Greenwood, SC
Price not published · $286,000 collections
General Dentistry
Price not published

Greenwood, SC

$286,000
Collections
3
Operatories
800
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Fort Mill, SC
Price not published · $245,169 collections
General Dentistry
Price not published

Fort Mill Area SC

$245,169
Collections
5
Operatories
More photos and details at JPA Dental Transitions →
Verified today
Columbia, SC
Price not published · $220,000 collections
General Dentistry
Price not published

Columbia, SC

$220,000
Collections
3
Operatories
873
Patients
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
Upstate SC, SC
Price not published · $72,641 collections
UNDER CONTRACTGeneral Dentistry
Price not published

Upstate SC-I77

$72,641
Collections
10
Operatories
More photos and details at JPA Dental Transitions →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

#9554 CHARLESTON AREA GP

4
Operatories
1,500
Sq Ft
More photos and details at ADS Dental Transitions →
Verified today
South Carolina
Price not published
Periodontics
Price not published

Upstate South Carolina Perio Practice for Sale

Contact broker for details
More photos and details at ADS Dental Transitions →
Verified today
Florence, SC
Price not published
General Dentistry
Price not published

Florence, SC

4
Operatories
Opens AFTCO's listings page →
Offered by
AFTCO
Verified today
South Carolina
Price not published
RE AVAILABLEGeneral Dentistry
Price not published

General Dentistry practice, SC

7
Operatories
Opens Bridgeway Transitions's listings page →
Verified today
Charleston, SC
Price not published
General Dentistry
Price not published

South Carolina General Dental Practice for Sale

Contact broker for details
Listed on dentaltown.com →
Verified today
Columbia Area, SC
Price not published
General Dentistry
Price not published

#9556 - COLUMBIA AREA

4
Operatories
Listed on dentaltown.com →
Verified today
Simpsonville, SC
Price not published
General Dentistry
Price not published

General Practice For Sale in East Columbia, South Carolina - off I-77

Contact broker for details
Listed on dentaltown.com →
Verified today
Greenville-Spartanburg, SC
Price not published
Endodontics
Price not published

Upstate South Carolina Endodontic Practice for Sale

Contact broker for details
Listed on dentaltown.com →
Verified today
Simpsonville, SC
Price not published
General Dentistry
Price not published

General practice for sale in Clay County, North Carolina

Contact broker for details
Listed on dentaltown.com →
Verified today
Columbia, SC
Price not published
General Dentistry
Price not published

Eastern Columbia, SC General Practice For Sale

4
Operatories
Listed on dentaltown.com →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

Red Bank & White Knoll, South Carolina Dental Office for Sale

Contact broker for details
Listed on dentaltown.com →
Verified today
Northeast South Carolina
Price not published
General Dentistry
Price not published

GP / Northeast SC SC / 1.3M / 6 Ops

6
Operatories
Listed on dentaltown.com →
Verified today
South Carolina
Price not published
Endodontics
Price not published

Endodontic Practice for Sale in Central South Carolina

Contact broker for details
Listed on dentaltown.com →
Verified today
Charleston, SC
Price not published
General Dentistry
Price not published

Family practice in North Charleston South Carolina

Contact broker for details
Listed on dentaltown.com →
Verified today
Murrells Inlet, SC
$450,000
General Dentistry
$450,000

Murrells Inlet, South Carolina

5
Operatories
More photos and details at Encompass Dental Practice Transitions →
Verified today
Myrtle Beach, SC
Price not published
General Dentistry
Price not published

Coastal NC SC

9
Operatories
More photos and details at Encompass Dental Practice Transitions →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

Statewide

Contact broker for details
More photos and details at PARAGON Dental Practice Transitions →
Verified today
Charleston, SC
Price not published
Oral Surgery
Price not published

Charleston Office For Sale/Lease

4,935
Sq Ft
Listed on scda.org →
Verified today
in Summerville, SC
Price not published
Oral Surgery
Price not published

OMS Office For Sale in Summerville

Contact broker for details
Listed on scda.org →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

Columbia Area GP For Sale

Contact broker for details
Listed on scda.org →
Verified today
or Lease, SC
Price not published
Orthodontics
Price not published

North Mt. Pleasant- Turnkey Office For Sale or Lease

2,770
Sq Ft
Listed on scda.org →
Verified today
Florence SC, SC
Price not published
General Dentistry
Price not published

Florence SC Practice For Sale

4
Operatories
1,800
Sq Ft
Listed on scda.org →
Verified today
in Pawleys Island, SC
$182,000
General Dentistry
$182,000

Office For Sale in Pawleys Island

6
Operatories
Listed on scda.org →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

Myrtle Beach, SC - Private Practice for Sale Market Common Dentistry

3,934
Sq Ft
Listed on scda.org →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

Eastern SC Office for Sale

7
Operatories
Listed on scda.org →
Verified today
South Carolina
Price not published
Periodontics
Price not published

Mt. Pleasant, SC - Fully Turnkey Periodontics Office in Dental Medical Office Park

4
Operatories
2,770
Sq Ft
More photos and details at US Dental Practices →
Verified today
Spartanburg, SC
Price not published
General Dentistry
Price not published

Dental Practice for Sale in Spartanburg

3
Operatories
1,350
Sq Ft
More photos and details at US Dental Transitions →
Verified today
South Carolina
Price not published
General Dentistry
Price not published

Perio Practice for Sale Outside of Charleston

5
Operatories
More photos and details at US Dental Transitions →
Verified today

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Nearby states

Practices currently listed in states bordering South Carolina.

Georgia109North Carolina111

Frequently asked questions

How many dental practices are for sale in South Carolina?

59 dental practices are publicly listed for sale in South Carolina on The Dental Practice Market, carried by 15 brokerages and dental association classifieds across 6 specialties. 1 was published in the last 7 days. Figures are rebuilt from broker sources daily and were current Oct 22, 2026.

Which South Carolina cities have dental practices for sale?

3 South Carolina cities have enough current listings for a page of their own: Columbia (5), Florence (3), Charleston (3). Practices are listed by metro area rather than street address, because the listing broker releases the practice identity only after a signed confidentiality agreement.

What kinds of dental practices are for sale in South Carolina?

South Carolina currently has 59 listed practices spanning 6 specialties. The largest groups are general dentistry (49), periodontics (3), endodontics (3). 1 of them mention the building or suite being available with the practice.

How do I see the address and financials of a South Carolina practice?

Each of the 59 South Carolina listings are anonymized to protect the seller. Every one links back to the broker who holds it; that broker releases the practice identity, full financials and tour details after you sign their confidentiality agreement. The Dental Practice Market never holds the address.

What does it cost to buy a dental practice in South Carolina?

Every practice on The Dental Practice Market carries the listing broker's own asking price — we don't set or estimate values, and we publish no averages or ranges. Price is driven by the practice's profit and cash flow, and most buyers finance the purchase through a bank or specialty dental lender. Open any of the 59 South Carolina listings to see that broker's asking price, then contact the broker for full financials.

How do I sell my dental practice in South Carolina?

The Dental Practice Market is a neutral marketplace — we don't list practices directly and we don't provide valuations. To sell, connect with a dental practice broker serving South Carolina through our broker directory; 15 sources are currently publishing South Carolina listings here. The broker handles valuation, confidential marketing and the sale.

Questions buyers ask

Direct answers, carrying the current numbers.

How many dental practices are for sale in the US?Which states have the most dental practices for sale?What types of dental practices are for sale?How do I buy a dental practice?Why are dental practice listings anonymous?
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Practice identity and location are never disclosed on this site. Contact the listing broker and sign an NDA for full details.